PT - JOURNAL ARTICLE AU - Annabathula, Rahul AU - Chen, Wengen AU - Jerome, Scott TI - High-Sensitivity Troponin Elevation in a Young Woman with Typical Chest Pain: The Heart of the Matter AID - 10.2967/jnmt.125.269733 DP - 2025 Jun 01 TA - Journal of Nuclear Medicine Technology PG - 169--171 VI - 53 IP - 2 4099 - http://tech.snmjournals.org/content/53/2/169.short 4100 - http://tech.snmjournals.org/content/53/2/169.full SO - J. Nucl. Med. Technol.2025 Jun 01; 53 AB - In the era of high-sensitivity troponin, minor elevations are often attributed to noncardiac etiologies. However, in patients who present with characteristic symptoms, any troponin elevation is concerning. We detail a case of a 37-y-old woman who presented to an outside hospital with typical chest pain and had a mild elevation in high-sensitivity troponin. Given her overall stability, she was discharged with outpatient cardiology follow-up. 82Rb PET/CT myocardial perfusion imaging test demonstrated a large, reversible anteroseptal perfusion defect. Coronary angiography revealed severe (80%) stenosis in the proximal left anterior descending artery treated with a single stent. This case highlights the need to have a high index of suspicion in young people with minor troponin elevations and pursue timely imaging.