PT  - JOURNAL ARTICLE
AU  - Annabathula, Rahul
AU  - Chen, Wengen
AU  - Jerome, Scott
TI  - High-Sensitivity Troponin Elevation in a Young Woman with Typical Chest Pain: The Heart of Matter
AID  - 10.2967/jnmt.125.269733
DP  - 2025 Apr 22
TA  - Journal of Nuclear Medicine Technology
PG  - jnmt.125.269733
4099  - http://tech.snmjournals.org/content/early/2025/04/22/jnmt.125.269733.short
4100  - http://tech.snmjournals.org/content/early/2025/04/22/jnmt.125.269733.full
AB  - In the era of high-sensitivity troponin, minor elevations are often attributed to noncardiac etiologies. However, in patients who present with characteristic symptoms, any troponin elevation is concerning. We detail a case of a 37-y-old woman who presented to an outside hospital with typical chest pain and had a mild elevation in high-sensitivity troponin. Given her overall stability, she was discharged with outpatient cardiology follow-up. 82Rb PET/CT myocardial perfusion imaging test demonstrated a large, reversible anteroseptal perfusion defect. Coronary angiography revealed severe (80%) stenosis in the proximal left anterior descending artery treated with a single stent. This case highlights the need to have a high index of suspicion in young people with minor troponin elevations and pursue timely imaging.