PT  - JOURNAL ARTICLE
AU  - Chandekar, Kunal Ramesh
AU  - Satapathy, Swayamjeet
AU  - Sharma, Ananya
AU  - Taneja, Neha
AU  - Tripathi, Madhavi
AU  - Bal, Chandrasekhar
TI  - Utility of <sup>18</sup>F-FDG PET/CT in Assessment of Disease Extent and Response to Treatment in Xanthoma Disseminatum
AID  - 10.2967/jnmt.123.266162
DP  - 2023 Dec 01
TA  - Journal of Nuclear Medicine Technology
PG  - 335--336
VI  - 51
IP  - 4
4099  - http://tech.snmjournals.org/content/51/4/335.short
4100  - http://tech.snmjournals.org/content/51/4/335.full
SO  - J. Nucl. Med. Technol.2023 Dec 01; 51
AB  - The clinical utility of 18F-FDG PET/CT is being increasingly recognized in histiocytic disorders. We report the case of a 23-y-old woman who presented with slowly progressive, yellowish-brown papules, plaques, and nodules over her face and flexures. Besides the multiple cutaneous lesions, lesions of the brain, stomach, gallbladder, and marrow were additionally revealed by baseline 18F-FDG PET/CT. Skin biopsy and the overall clinical picture were consistent with xanthoma disseminatum. Subsequent PET/CT after cladribine therapy revealed a decrease in the extent and metabolic activity of most lesions, suggestive of a favorable response. This case report highlights the potential role of 18F-FDG PET/CT in the accurate assessment of disease extent and posttreatment response in rare histiocytic disorders.