PT  - JOURNAL ARTICLE
AU  - Chalikandy, Ashwini
AU  - Yadav, Subhash
AU  - Basu, Sandip
TI  - Differentiation of Discordant Lesions on Dual-Tracer PET/CT (<sup>68</sup>Ga-PSMA-11 and <sup>18</sup>F-FDG) in Prostate Carcinoma: Diagnosis of Second Primary Malignancies
AID  - 10.2967/jnmt.123.265779
DP  - 2023 Aug 16
TA  - Journal of Nuclear Medicine Technology
PG  - jnmt.123.265779
4099  - http://tech.snmjournals.org/content/early/2023/08/16/jnmt.123.265779.short
4100  - http://tech.snmjournals.org/content/early/2023/08/16/jnmt.123.265779.full
AB  - We present 2 cases of metastatic castration-resistant prostate carcinoma with discordant lesions on dual-tracer PET/CT (68Ga-PSMA-11 and 18F-FDG PET/CT), which on subsequent histopathologic evaluation revealed second primary malignancies of combined hepatocellular carcinoma and cholangiocarcinoma and poorly differentiated squamous cell carcinoma. These case illustrations emphasize the need to evaluate discordant lesions on dual-tracer PET/CT, which can lead to early diagnosis of second primary malignancies and thereby can provide better management in these patients.