TY - JOUR T1 - <sup>177</sup>Lu-PSMA Therapy JF - Journal of Nuclear Medicine Technology JO - J. Nucl. Med. Technol. SP - 205 LP - 212 DO - 10.2967/jnmt.122.263814 VL - 50 IS - 3 AU - Ephraim E. Parent AU - Bital Savir-Baruch AU - Isis W. Gayed AU - Frankis Almaguel AU - Bennett B. Chin AU - Austin R. Pantel AU - Evan Armstrong AU - Amanda Morley AU - Robin C. Ippisch AU - Robert R. Flavell Y1 - 2022/09/01 UR - http://tech.snmjournals.org/content/50/3/205.abstract N2 - Radiopharmaceutical therapy using 177Lu-prostate-specific membrane antigen (PSMA) is an effective prostate cancer treatment that was recently approved by the U.S. Food and Drug Administration. This method leverages the success of PSMA-targeted PET imaging, enabling delivery of targeted radiopharmaceutical therapy; has demonstrated a clear benefit in large prospective clinical trials; and promises to become part of the standard armamentarium of treatment for patients with prostate cancer. This review highlights the evidence supporting the use of this agent, along with important areas under investigation. Practical information on technology aspects, dose administration, nursing, and the role of the treating physician is highlighted. Overall, 177Lu-PSMA treatment requires close collaboration among referring physicians, nuclear medicine technologists, radiopharmacists, and nurses to streamline patient care. ER -