PT  - JOURNAL ARTICLE
AU  - Rahul V Parghane
AU  - Sandip Basu
TI  - <sup>18</sup>F-FDG PET/CT vs. <sup>68</sup>Ga-PSMA-11 PET/CT in evaluation of distant metastatic disease in recurrent Renal Cell Carcinoma
AID  - 10.2967/jnmt.122.264014
DP  - 2022 Aug 01
TA  - Journal of Nuclear Medicine Technology
PG  - jnmt.122.264014
4099  - http://tech.snmjournals.org/content/early/2022/08/30/jnmt.122.264014.short
4100  - http://tech.snmjournals.org/content/early/2022/08/30/jnmt.122.264014.full
AB  - The prostate-specific membrane antigen (PSMA) expression has been observed in neo-vasculature of various malignancies. We present a case of metastatic renal cell carcinoma (RCC), with comparative FDG-PET/CT and 68Ga-PSMA-11 imaging, in which FDG-PET/CT failed to detect metastatic thyroid disease and showed less FDG concentrating lesions in other sites, while 68Ga-PSMA-11 PET/CT scan identified metastatic thyroid disease and demonstrated intensely PSMA expressing distant metastatic lesions. Thus 68Ga-PSMA-11 PET/CT may be contemplated a potentially useful imaging technique to detect metastasis and also to guide choice of specific treatments like PSMA-based radionuclide therapy in patients with recurrent metastatic RCC.