TY - JOUR T1 - PET/MRI, Part 4: Clinical Applications JF - Journal of Nuclear Medicine Technology JO - J. Nucl. Med. Technol. SP - 90 LP - 96 DO - 10.2967/jnmt.121.263288 VL - 50 IS - 2 AU - Geoffrey M. Currie AU - Jose Leon AU - Elad Nevo AU - Peter Kamvosoulis Y1 - 2022/06/01 UR - http://tech.snmjournals.org/content/50/2/90.abstract N2 - CE credit: For CE credit, you can access the test for this article, as well as additional JNMT CE tests, online at https://www.snmmilearningcenter.org. Complete the test online no later than June 2025. Your online test will be scored immediately. You may make 3 attempts to pass the test and must answer 75% of the questions correctly to receive Continuing Education Hour (CEH) credit. Credit amounts can be found in the SNMMI Learning Center Activity. SNMMI members will have their CEH credit added to their VOICE transcript automatically; nonmembers will be able to print out a CE certificate upon successfully completing the test. The online test is free to SNMMI members; nonmembers must pay $15.00 by credit card when logging onto the website to take the test.PET/MRI as a hybrid modality provides novel imaging opportunities. Although there is a very broad array of diseases that could benefit from PET/MRI, there is only a narrow range of applications for which the benefit over standard care justifies the higher resource use and, in particular, offers a net positive trade-off over PET/CT. This benefit is generally associated with the omission of CT and the associated radiation dose from the patient workup. This article summarizes the generally accepted clinical applications of PET/MRI in both adult and pediatric populations. Although there are several potential applications and certainly exciting research that may expand applications in the future, the purpose of this paper was to focus on current, mainstream applications. This is the final article in a 4-part integrated series sponsored by the PET/MR and Publication Committees of the Society of Nuclear Medicine and Molecular Imaging–Technologist Section. ER -