RT Journal Article SR Electronic T1 Biology of Cancer and PET Imaging: Pictorial Review JF Journal of Nuclear Medicine Technology JO J. Nucl. Med. Technol. FD Society of Nuclear Medicine SP jnmt.121.263534 DO 10.2967/jnmt.121.263534 A1 Ismet Sarikaya YR 2022 UL http://tech.snmjournals.org/content/early/2022/05/24/jnmt.121.263534.abstract AB Development and spread of cancer is a multi-step and complex process which involves number of alterations, interactions and molecular networks. PET imaging is closely related with biology of cancer as it detects the cancer based on biological and pathological changes in tumor cells and tumor microenvironment. In this review article, biology of development and spread of cancer and role of PET imaging in Oncology was summarized and supported with various PET images demonstrating cancer spread patterns.