PT - JOURNAL ARTICLE AU - Ismet Sarikaya TI - Biology of Cancer and PET Imaging: Pictorial Review AID - 10.2967/jnmt.121.263534 DP - 2022 Apr 01 TA - Journal of Nuclear Medicine Technology PG - jnmt.121.263534 4099 - http://tech.snmjournals.org/content/early/2022/04/19/jnmt.121.263534.short 4100 - http://tech.snmjournals.org/content/early/2022/04/19/jnmt.121.263534.full AB - Development and spread of cancer is a multi-step and complex process which involves number of alterations, interactions and molecular networks. PET imaging is closely related with biology of cancer as it detects the cancer based on biological and pathological changes in tumor cells and tumor microenvironment. In this review article, biology of development and spread of cancer and role of PET imaging in Oncology was summarized and supported with various PET images demonstrating cancer spread patterns.