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OtherImaging (JNMT)

Nuclear Medicine and Molecular Imaging in Nodal Staging and Surveillance of Ocular Melanoma: Cases Report and Review of Literature

Kenneth S. Zurcher, Odette M. Houghton, Joanne F. Shen, Mahesh Seetharam, Michael C. Roarke and Ming Yang
Journal of Nuclear Medicine Technology April 2021, jnmt.120.260539; DOI: https://doi.org/10.2967/jnmt.120.260539
Kenneth S. Zurcher
Mayo Clinic Arizona, United States
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Odette M. Houghton
Mayo Clinic Arizona, United States
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Joanne F. Shen
Mayo Clinic Arizona, United States
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Mahesh Seetharam
Mayo Clinic Arizona, United States
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Michael C. Roarke
Mayo Clinic Arizona, United States
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Ming Yang
Mayo Clinic Arizona, United States
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Abstract

Ocular melanoma (OM) is a rare noncutaneous malignancy and consists of 2 different subtypes based on anatomic location in the eye: uveal melanoma (UM) and conjunctival melanoma (CM). As in cutaneous melanoma, nuclear medicine and molecular imaging play valuable roles in the nodal staging and clinical management of OM. Through the illustration of 2 distinctive cases, we aim to demonstrate the complementary roles of standard lymphoscintigraphy, advanced single-photon emission computed tomography/computed tomography, 18F-fludeoxyglucose positron emission tomography/computed tomography, and hybrid positron emission tomography/magnetic resonance imaging in accurate nodal staging and surveillance of OM. We also review the epidemiology, existing staging guidelines and management of UM and CM.

  • Lymphoscintigraphy
  • Oncology: Melanoma
  • PET/CT
  • PET/MRI
  • FDG/PET
  • SPECT
  • conjunctival melanoma
  • lymphoscintigraphy
  • uveal melanoma

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Journal of Nuclear Medicine Technology: 49 (1)
Journal of Nuclear Medicine Technology
Vol. 49, Issue 1
March 1, 2021
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Nuclear Medicine and Molecular Imaging in Nodal Staging and Surveillance of Ocular Melanoma: Cases Report and Review of Literature
Kenneth S. Zurcher, Odette M. Houghton, Joanne F. Shen, Mahesh Seetharam, Michael C. Roarke, Ming Yang
Journal of Nuclear Medicine Technology Apr 2021, jnmt.120.260539; DOI: 10.2967/jnmt.120.260539

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Nuclear Medicine and Molecular Imaging in Nodal Staging and Surveillance of Ocular Melanoma: Cases Report and Review of Literature
Kenneth S. Zurcher, Odette M. Houghton, Joanne F. Shen, Mahesh Seetharam, Michael C. Roarke, Ming Yang
Journal of Nuclear Medicine Technology Apr 2021, jnmt.120.260539; DOI: 10.2967/jnmt.120.260539
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Keywords

  • lymphoscintigraphy
  • Oncology: Melanoma
  • PET/CT
  • PET/MRI
  • FDG/PET
  • SPECT
  • conjunctival melanoma
  • uveal melanoma
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