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OtherQuality & Practice Management (JNMT)

Yttrium-90 positron emission tomography for qualitative and quantitative assessment of residual activity in delivery apparatus after radioembolization

Yung Hsiang Kao, Alicia Corlett, Katrina Jorna, Alexander Rhodes and Dinesh Sivaratnam
Journal of Nuclear Medicine Technology December 2020, jnmt.120.258251; DOI: https://doi.org/10.2967/jnmt.120.258251
Yung Hsiang Kao
1 The Royal Melbourne Hospital, Australia;
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Alicia Corlett
1 The Royal Melbourne Hospital, Australia;
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Katrina Jorna
2 Cabrini Hospital, Australia
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Alexander Rhodes
1 The Royal Melbourne Hospital, Australia;
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Dinesh Sivaratnam
1 The Royal Melbourne Hospital, Australia;
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Abstract

Assessment of residual activity is critical for quality assurance after yttrium-90 radioembolization. The resin microsphere manufacturer’s indirect method of estimating the residual activity is laborious and vulnerable to inaccuracies. Furthermore, their method cannot localize the exact site of residual activity. Yttrium-90 PET/CT for qualitative and quantitative assessment of residual activity has not been described. We show an example of yttrium-90 PET/CT of residual activity in the delivery apparatus and catheters packed inside the delivery box. Focally intense residual activity was clearly localized to the stopcock junction. Residual activity was directly quantified by setting the PET volume-of-interest isocontour threshold to 1%.

  • PET/CT
  • Quality Assurance
  • Radionuclide Therapy
  • PET/CT
  • SIR-Spheres
  • radioembolization
  • selective internal radiation therapy
  • yttrium-90

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Journal of Nuclear Medicine Technology: 48 (4)
Journal of Nuclear Medicine Technology
Vol. 48, Issue 4
December 1, 2020
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Yttrium-90 positron emission tomography for qualitative and quantitative assessment of residual activity in delivery apparatus after radioembolization
Yung Hsiang Kao, Alicia Corlett, Katrina Jorna, Alexander Rhodes, Dinesh Sivaratnam
Journal of Nuclear Medicine Technology Dec 2020, jnmt.120.258251; DOI: 10.2967/jnmt.120.258251

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Yttrium-90 positron emission tomography for qualitative and quantitative assessment of residual activity in delivery apparatus after radioembolization
Yung Hsiang Kao, Alicia Corlett, Katrina Jorna, Alexander Rhodes, Dinesh Sivaratnam
Journal of Nuclear Medicine Technology Dec 2020, jnmt.120.258251; DOI: 10.2967/jnmt.120.258251
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Keywords

  • PET/CT
  • Quality Assurance
  • Radionuclide Therapy
  • SIR-Spheres
  • radioembolization
  • selective internal radiation therapy
  • yttrium-90
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