The oral route is the most widely used and preferable way of drug administration. Several
pharmacokinetic processes play a role in the distribution of administered drugs. Therefore …

Obesity is a phenotype resulting from a series of causative factors with a variable risk of
complications. Etiologic diversity requires personalized prevention and treatment. Imaging …

Targeting of the human ribosome is an unprecedented therapeutic modality with a genome‐
wide selectivity challenge. A liver‐targeted drug candidate is described that inhibits …

Intravenous access is difficult in some patients referred for 18F-FDG PET imaging.
Extravasation at the injection site and accumulation in central catheters can lead to limited …

Interventions affecting gastrointestinal (GI) physiology suggest that the GI tract plays an
important role in modulating the uptake of ingested glucose by body tissues. We aimed at …

Abstract 18 F-FDG is the most commonly used radioisotope in PET scanning and is
administered intravenously. When patients cannot cannulated, there are limited options …

This chapter describes the discovery and early development of small molecule proprotein
convertase subtilisin/kexin type 9 (PCSK9) inhibitors. The discovery of the primary molecular …

Introdução: PET/TC com 18F-FDG em oncologia é um excelente método para estadiamento,
resposta terapêutica e avaliação de doença residual nas neoplasias de alto grau. A …