Incremental value of ischemic stunning on the detection of severe and extensive coronary artery disease in dipyridamole Tl-201 gated myocardial perfusion imaging

Int J Cardiol. 2005 Oct 20;105(1):108-10. doi: 10.1016/j.ijcard.2004.11.018.

Abstract

The sensitivity of nuclear myocardial perfusion imaging in detecting coronary artery disease is high. However, false-negative results may be encountered if all the myocardial territories were uniformly affected. Ischemic stunning after dipyridamole-stress on gated SPECT may be an indicator of severe and extensive coronary artery disease, and can help the interpretation of borderline perfusion images and the elimination of false-negatives secondary to relatively balanced lesions in three-vessel disease.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged
  • Coronary Artery Disease / diagnosis*
  • Coronary Artery Disease / diagnostic imaging
  • Coronary Artery Disease / physiopathology
  • Dipyridamole*
  • Humans
  • Male
  • Myocardial Reperfusion
  • Myocardial Stunning / diagnosis*
  • Myocardial Stunning / diagnostic imaging
  • Myocardial Stunning / physiopathology
  • Sensitivity and Specificity
  • Stroke Volume / physiology
  • Thallium Radioisotopes*
  • Tomography, Emission-Computed, Single-Photon
  • Ventricular Function, Left / physiology

Substances

  • Thallium Radioisotopes
  • Dipyridamole