RT Journal Article
SR Electronic
T1 Importance of Gated Imaging in Both Phases of Myocardial Perfusion SPECT: Myocardial Stunning After Dipyridamole Infusion
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 88
OP 91
VO 34
IS 2
A1 Vahidreza Dabbagh Kakhki
A1 Seyed Rasoul Zakavi
A1 Ramin Sadeghi
A1 Ahmad Yousefi
YR 2006
UL http://tech.snmjournals.org/content/34/2/88.abstract
AB We present the case report of a 72-y-old woman who underwent 99mTc-sestamibi gated myocardial perfusion SPECT with a 2-d protocol. SPECT images revealed ischemia of the apical, anteroapical, apicoseptal, and septal walls. Postdipyridamole gated SPECT revealed significant deterioration in the left ventricular ejection fraction (LVEF), wall motion, and systolic wall thickening relative to the findings obtained with rest gated SPECT. Myocardial stunning is a lingering contractile dysfunction that occurs after a brief ischemic insult. Myocardial stunning after dynamic exercise or pharmacologic stress tests has been demonstrated. Thus, the use of gated SPECT in both phases of perfusion studies may add useful information about cardiac function, as a poststress study alone probably reflects stunned myocardium in some patients undergoing ischemic stress tests. The difference between poststress LVEF and rest LVEF may have a powerful impact on prognosis, as it seems to depend on the extent and severity of induced ischemia.