Skip to main content

Main menu

  • Home
  • Content
    • Current
      • JNMT Supplement
    • Ahead of print
    • Past Issues
    • Continuing Education
    • JNMT Podcast
    • SNMMI Annual Meeting Abstracts
  • Subscriptions
    • Subscribers
    • Rates
    • Journal Claims
    • Institutional and Non-member
  • Authors
    • Submit to JNMT
    • Information for Authors
    • Assignment of Copyright
    • AQARA Requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
    • Corporate & Special Sales
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • SNMMI
    • JNMT
    • JNM
    • SNMMI Journals
    • SNMMI

User menu

  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Nuclear Medicine Technology
  • SNMMI
    • JNMT
    • JNM
    • SNMMI Journals
    • SNMMI
  • Subscribe
  • My alerts
  • Log in
  • My Cart
Journal of Nuclear Medicine Technology

Advanced Search

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • Continuing Education
    • JNMT Podcast
    • SNMMI Annual Meeting Abstracts
  • Subscriptions
    • Subscribers
    • Rates
    • Journal Claims
    • Institutional and Non-member
  • Authors
    • Submit to JNMT
    • Information for Authors
    • Assignment of Copyright
    • AQARA Requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
    • Corporate & Special Sales
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • Watch or Listen to JNMT Podcast
  • Visit SNMMI on Facebook
  • Join SNMMI on LinkedIn
  • Follow SNMMI on Twitter
  • Subscribe to JNMT RSS feeds
Research ArticleInvited Perspective

Using Intragastric Meal Distribution and Antral Contractility for Enhanced Gastric Emptying Analysis

Patrick M. Colletti
Journal of Nuclear Medicine Technology June 2019, 47 (2) 137; DOI: https://doi.org/10.2967/jnmt.118.225029
Patrick M. Colletti
Keck School of Medicine of USC, Los Angeles, California
FACNM, FSNMMI
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
  • PDF
Loading

See the associated article on page 138.

In this issue of Journal of Nuclear Medicine Technology, Orthey et al. (1) investigate the dynamic relationship of the fundal reservoir and the antral pump in solid-meal gastric physiology in 20 healthy volunteers. Special attention was focused on dynamic antral contraction scintigraphy (DACS). Interestingly, “For the DACS imaging, each subject was allowed to choose whether an upright standing or seated position was most comfortable and then instructed to remain as still as possible in that position for the 20 min of DACS imaging.” No further comment on any potential differences in upright versus supine gastric emptying were presented, despite the obvious gravitational advantage of the upright position for fundal emptying, given that the authors were interested in isolated antral function.

Antral contractions may of course be directly visualized nonquantitatively via fluoroscopy with nonphysiologic barium suspensions or iodinated contrast agents, and elastogastrography may be used for antral frequency analysis (2). Because the normal antrum contracts at about 3 cycles per minute during gastric emptying, antral frequency analysis cannot be determined by routine 1-image-per-minute solid gastric-emptying examinations.

On the other hand, for this gastric-emptying study, antral contractions were monitored at the relatively rapid rate of 1 image per 3 s (3–5), and thus, the acquired data time resolution far exceeded the standard 1-image-per-minute acquisition rate typically used. This rapid, dynamic data collection was then frequency-analyzed using fast Fourier techniques to identify a relatively novel physiologically determined gastric antral region of interest, as compared with the more usually selected arbitrary anatomic mid-stomach fundal–antral border.

The onset and frequency of antral contractions could then be identified and measured, and a normal database created. Authors speculate on the potential clinical benefits of dynamic antral contraction analysis as compared with routine gastric-emptying examinations. Perhaps in the future we will collect and manage gastric-emptying data in a manner similar to first-pass radionuclide angiography, with antral ejection fraction and phase analysis and reporting. We should look forward to the results of future clinical trials targeting the application of antral function analysis to outcomes in patients with dyspepsia.

DISCLOSURE

No potential conflict of interest relevant to this article was reported.

Footnotes

  • Published online Apr. 24, 2019.

REFERENCES

  1. 1.↵
    1. Orthey P,
    2. Dadparvar S,
    3. Parkman HP,
    4. Maurer AH
    . Enhanced gastric emptying scintigraphy to assess fundic accommodation using intragastric meal distribution and antral contractility. J Nucl Med Technol. 2019;47:138–143.
    OpenUrlAbstract/FREE Full Text
  2. 2.↵
    1. Parkman HP,
    2. Hasler WL,
    3. Barnett JL,
    4. Eaker EY
    ; American Motility Society Clinical GI Motility Testing Task Force. Electrogastrography: a document prepared by the Gastric Section of the American Motility Society Clinical GI Motility Testing Task Force. Neurogastroenterol Motil. 2003;15:89–102.
    OpenUrlCrossRefPubMed
  3. 3.↵
    1. Urbain JL,
    2. Vekemans MC,
    3. Bouillon R,
    4. et al
    . Characterization of gastric antral motility disturbances in diabetes using a scintigraphic technique. J Nucl Med. 1993;34:576–581.
    OpenUrlAbstract/FREE Full Text
  4. 4.
    1. Parkman HP,
    2. Miller MA,
    3. Trate DM,
    4. et al
    . Effect of gastric acid suppressants on human gastric motility. Gut. 1998;42:243–250.
    OpenUrlAbstract/FREE Full Text
  5. 5.↵
    1. Parkman HP,
    2. Trate DM,
    3. Knight LC,
    4. Brown KL,
    5. Maurer AH,
    6. Fisher RS
    . Cholinergic effects on human gastric motility. Gut. 1999;45:346–354.
    OpenUrlAbstract/FREE Full Text
  • Received for publication January 21, 2019.
  • Accepted for publication January 30, 2019.
PreviousNext
Back to top

In this issue

Journal of Nuclear Medicine Technology: 47 (2)
Journal of Nuclear Medicine Technology
Vol. 47, Issue 2
June 1, 2019
  • Table of Contents
  • About the Cover
  • Index by author
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Journal of Nuclear Medicine Technology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Using Intragastric Meal Distribution and Antral Contractility for Enhanced Gastric Emptying Analysis
(Your Name) has sent you a message from Journal of Nuclear Medicine Technology
(Your Name) thought you would like to see the Journal of Nuclear Medicine Technology web site.
Citation Tools
Using Intragastric Meal Distribution and Antral Contractility for Enhanced Gastric Emptying Analysis
Patrick M. Colletti
Journal of Nuclear Medicine Technology Jun 2019, 47 (2) 137; DOI: 10.2967/jnmt.118.225029

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Using Intragastric Meal Distribution and Antral Contractility for Enhanced Gastric Emptying Analysis
Patrick M. Colletti
Journal of Nuclear Medicine Technology Jun 2019, 47 (2) 137; DOI: 10.2967/jnmt.118.225029
Twitter logo Facebook logo LinkedIn logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • DISCLOSURE
    • Footnotes
    • REFERENCES
  • Info & Metrics
  • PDF

Related Articles

  • Enhanced Gastric Emptying Scintigraphy to Assess Fundic Accommodation Using Intragastric Meal Distribution and Antral Contractility
  • PubMed
  • Google Scholar

Cited By...

  • Distinct subgroups in gastroparesis defined by simultaneous body surface gastric mapping and gastric emptying breath testing
  • Readers Help to Shape JNMT Content
  • Google Scholar

More in this TOC Section

  • Navigating a Transatlantic Career Shift: Guidance for U.S. Nuclear Medicine Technologists Looking to Relocate to the U.K.
  • Ventilation/Perfusion Lung Scan Safety Statement in the Current Coronavirus Disease 2019 Environment
  • The Rise of Cardiac Amyloidosis Imaging
Show more Invited Perspective

Similar Articles

SNMMI

© 2025 SNMMI

Powered by HighWire