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Quality Control Validation for Exogenous Natural Surfactant Labeled with 99mTc

Gabriela P. Calmanovici, PhD1, María J. Salgueiro, Bioch, Pharm1, Natalia M. Leonardi, Bioch1, Cinthia G. Goldman, Bioch, Pharm1, Jorge O. Nicolini, Bioch2, Jose R. Boccio, PhD3, Ricardo A. Caro, PhD2, Patricia D. Zubata, Pharm4 and Marcela B. Zubillaga, PhD1

1 Radioisotopes Laboratory, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina;
2 Laboratorios Bacon S.A.I.C., Buenos Aires, Argentina;
3 Physics Department, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina;
4 Quality Control Department, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina



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  		FIGURE 1. Linearity evaluation for chromatographic studies. AC = activity concentration of 99mTc-ENS; A origin = activity at origin of acetone/Whatman-1 paper chromatography.

 


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  		FIGURE 2. Linearity evaluation for biodistribution studies. AC = activity concentration of 99mTc-ENS; A lungs = activity in lungs in biodistribution studies.

 




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