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Utility of ¹⁸F-FDG PET in Evaluating Cancers of Lung^*

Nuclear Medicine Division, Department of Diagnostic Imaging, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada

View larger version (46K): [in a new window]   FIGURE 1. (A) CT scan identifies a nonspecific nodule in right lung (arrow). (B) Axial view at same level from the PET scan demonstrates markedly increased 18F-FDG uptake in lung nodule (arrow), which proved to be lung cancer.

View larger version (55K): [in a new window]   FIGURE 2. Maximum-intensity-projection image from 18F-FDG PET scan demonstrates intense uptake in known lung cancer in left upper lobe (arrow) as well as within 2 small ipsilateral mediastinal lymph nodes (arrowheads). Importantly, PET scan does not show abnormalities more distally.

View larger version (46K): [in a new window]   FIGURE 3. (A) CT scan demonstrates new nodule in left lower lobe (arrowhead). (B) CT scan also demonstrates a larger area of more ill-defined opacification in left lung (arrowheads). (C) Maximum-intensity-projection image from PET scan shows intense 18F-FDG uptake in nodule at left base (arrow), consistent with recurrent cancer. Larger abnormality has only mildly increased 18F-FDG uptake (arrowheads) and is consistent with radiation change.

View larger version (24K): [in a new window]   FIGURE 4. CT (A), PET (B), and fused PET/CT (C) images of patient with lung cancer. There is avid 18F-FDG uptake within lymph nodes on both sides of mediastinum (arrowheads). Fusion with CT scan helps accurately localize abnormal 18F-FDG activity, distinguishing malignant lymph nodes from normal structures in region.