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Measurement of 18F-FDG Concentrations in Blood Samples: Comparison of Direct Calibration and Standard Solution Methods

Henri N.J.M. Greuter1, Ronald Boellaard, PhD1, Arthur van Lingen, PhD1, Eric J.F. Franssen, PharmD, PhD1,2 and Adriaan A. Lammertsma, PhD1

1PET Center, VU University Medical Center, Amsterdam, The Netherlands;
2Department of Pharmacy, VU University Medical Center, Amsterdam, The Netherlands



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FIGURE 1. Ratio of activity concentration (AC) determined with standard solution and calibration factor method for 1 y. Slightly declining slope indicates that adjustment of calibration factors is required about yearly.

 


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FIGURE 2. Ratio of activity concentration (AC) standard/calibration factor methods versus mass of patient dose. Observed large variation in this ratio is explained by uncertainties of measurements, which were required for preparation of standard solutions.

 





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