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Molecular Imaging: ¹⁸F-FDG PET and a Whole Lot More^*

¹ Institute of Imaging Science, Departments of Radiology and Radiological Sciences, Vanderbilt University, Nashville, Tennessee; ² Departments of Physics and Astronomy, Vanderbilt University, Nashville, Tennessee; ³ Department of Chemical and Physical Biology, Vanderbilt University, Nashville, Tennessee; ⁴ Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee; and ⁵ Department of Neurosurgery, Vanderbilt University, Nashville, Tennessee

Correspondence: Please address correspondence to: Todd E. Peterson, Vanderbilt University Institute of Imaging Science, 1161 21st Ave. S., AA 1105 MCN, Nashville, TN 37232-2310. E-mail: todd.e.peterson{at}vanderbilt.edu

ABSTRACT

The intention of this review is to provide information about the rapidly evolving field of molecular imaging and its potential impact on the clinical practice of nuclear medicine. On completing this article the reader should be able to define molecular imaging, describe the ways in which molecular imaging can be used, identify some of the biologic processes that can be targeted with molecular imaging agents, and list the modalities that can be used for molecular imaging, along with the strengths and weaknesses of each.

Key Words: instrumentation; molecular imaging; oncology; contrast agents; nonnuclear imaging methods