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¹⁸F-FDG Imaging: Pitfalls and Artifacts^*

Nuclear Medicine Department, University at Buffalo, Buffalo, New York

ABSTRACT

¹⁸F-FDG PET is emerging as a useful tool in the staging and restaging of many malignant neoplasms, such as lymphoma, lung cancer, colorectal cancer, head and neck cancer, breast cancer, and melanoma. To accurately interpret ¹⁸F-FDG findings one must be familiar with the normal physiologic distribution of the tracer, frequently encountered physiologic variants, and benign pathologic causes of ¹⁸F-FDG uptake that can be confused with a malignant neoplasm. The objectives of this article are to (a) describe the mechanism of ¹⁸F-FDG uptake, (b) list the patient preparation and pertinent patient history before ¹⁸F-FDG imaging, (c) describe the whole-body physiologic distribution of ¹⁸F-FDG, (d) list and discuss normal physiologic variants, and (e) list and discuss benign pathologic causes of ¹⁸F-FDG uptake.

Key Words: ¹⁸F-FDG imaging; artifacts

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