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Nonosseous Abnormalities on Bone Scans*

Department of Nuclear Medicine, Faculty of Medicine, Kuwait University, Safat, Kuwait; and Department of Nuclear Medicine, Mubarak Al-Kabeer Hospital, Ministry of Health, Jabriya, Kuwait

ABSTRACT

Although bone scanning is a test primarily concerned with skeletal abnormalities, important nonosseous findings are occasionally present on the images. To gauge the significance of such nonosseous uptake and, in particular, to determine whether these findings contain useful diagnostic information, the technical and medical staff in nuclear medicine must recognize the various patterns of nonbony uptake and understand their causes. The objectives of this article are to demonstrate the appearances of nonosseous uptake on bone scans, to categorize the forms of soft-tissue uptake, to emphasize technical artifacts leading to soft-tissue uptake, and to highlight the clinical significance of pathologic soft-tissue uptake.

Key Words: bone scintigraphy; breast cancer; renal cell carcinoma; malignant pleural effusion